E. H. B., 8h27m A. M. To 4h27m P. M., April 8, 1907. 72.9 Kilograms

Urinated 6h50m a. m. and 4h27m p. m.; took enema about 7h45m a. m. More or less activity in first period in connection with receiving beef tea and dishes, as subject was obliged to go to food aperture several times. Very quiet in last part of first period and in second period, but not so quiet in fourth period. Reading greater part of time; occasionally drowsy. Drank 134 grams water in fourth period. Body-temperature: 36.57°, 36.50°, 36.57°, 36.61°, and 36.66° C. Pulse rate, 51; respiration rate, 18. Beef tea heated to about 80° C. in preparation. Creatinine in beef tea, 0.0121 gram in 100 c.c; creatine,1 0.109 gram in 100 c.c.

A. H. M., 8h44m A. M. To 4h4m P. M., April 29, 1907. 67.4 Kilograms

Urinated 6, 9h47ra, 10h54m a. m., 2h53m and 5h20m p. m. Somewhat restless in first and third periods; more quiet in second and fourth periods; much of time reading. Body-temperature: 36.70°, 36.51°, 36.38°, 36.22°, and 36.42° C. Pulse rate, 60; respiration rate, 20.

A. W. W., 8h24m A. M. To 4h24m P. M., May 2, 1907. 58.4 Kilograms

Urinated 7h40m, 9h40m, 10h32m a. m., 12h28m, 2h32m, and 4h35m p. m. Felt cold after taking both portions of beef tea. Considerable activity in telephoning and getting beef tea from food aperture, but after 9h06m a. m. subject sat quietly and read; very quiet in other periods. Drank water at beginning of fourth period (30 grams). Body-temperature: 36.41°, 36.60°, 36.64°, 36.76°, and 36.75° C. Pulse rate, 61; respiration rate, 20. Creatinine in beef tea, 0.011 gram in 100 c.c; creatine,1 0.161 gram in 100 c.c.

A. W. W., 8h25m A. M. To 4h25m P. M., May 9, 1907. 58.8 Kilograms

Urinated 7h40m a. m. (after enema), 12h32m and 4h34m p. m. Very quiet in first period after 9 o'clock, also in second and fourth periods; in third period, somewhat more active. Perspired very freely for a short time after drinking beef tea. Drank water at beginning of both second and third periods (216 grams). Body-temperature: 36.62°, 36.75°, and 36.88° C. Pulse rate, 62; respiration rate, 21. Beef tea used was of double strength and not heated above 40° C. in making. Coagulated somewhat when reheated to about 75° C. before serving. Creatinine in beef tea, 0.018 gram in 100 c.c; creatine,1 0.211 gram in 100 c.c.

1Expressed as creatinine.

A. H. M., 8h24m A.m. To 4h24m P.m., May 10, 1907. 66.7 Kilograms

Beef tea used for this experiment same as that used for A. W. W., May 9, 1907, but not heated to so high a temperature for serving; no coagulation. Subject urinated 7, 10h28m a. m., 12h36m and 4h32m p. m. Very quiet, read greater part of time. Telephoned and opened food aperture at 8h32m a. m. Body-temperature: 36.62°, 36.51°, 36.49°, 36.74°, and 36.68° C. Pulse rate, 59; respiration rate, 18.

J. J. C, 9h02m A. M. To 3h49m P. M., May 12, 1910. 64.7 Kilograms

Urinated at 6h55m, 9h41m, llh04m, llh53m a. m. and lh45m p. m. Slept considerable part of experiment; slept 10 minutes in first basal period, 10 minutes in second period, and about half of first period after beef tea. Awakened by observer and to prevent his falling asleep again was told to ring telephone bell every 5 minutes as evidence of being awake. Fell asleep at lh42m p. m. (in third period after beef tea), also at 3h44m p. m. (in fifth period). Moved considerably at lh43m p. m. Basal periods: body-temperature, 36.81°, 36.57°, 36.58° C; pulse rate, 64; respiration rate, 19. Periods after beef tea: body-temperature, 36.85°, 36.81°, 36.85°, 36.79°, and 36.71° C; pulse rate, 65; respiration rate, 20. Both pulse and respiration records are lacking for a part of the experiment.

J. R., 8h57m A. M. To Sw P. M., May 13, 1910. 69.5 Kilograms

Took enema before entering apparatus. During basal periods telephoned once; at end of second period complained of pain in stomach. After taking beef tea, had nausea and drank water (28 grams). During periods after beef tea did not feel well; was restless, telephoned several times, drank water (37 grams) in first period, urinated in second period and again at 3h40m p. m. (after experiment). Basal periods: pulse rate, 65; respiration rate, 15. Periods after beef tea: pulse rate, 68; respiration rate, 16.

Table 88. - E. H. B., April 8, 1907. Sitting. (2-Hour Periods). Beef Tea (82.5° C)

Amount, 892 grams; nitrogen, 1.61 grams; total energy, 71 cals.

Fuel value: Total, 57 cals.; from protein, 72 p. ct.; from fat, 15 p. ct.; from carbohydrates, 13 p. ct.

Nitrogen in urine, 0.72 gram per 2 hours.2 Basal values (March 7 and 13, 1907): CO2, 58 grams; O2, 48 grams; heat, 179 cals.

Time elapsed since subject finished eating.

Carbon dioxide.

Oxygen.

Heat.

Total.

Increase.

Total.

Increase.

Total.

Increase.

grams.

grama.

grama.

grams.

cola.

cals.

0 to 2 hours3..

63

5

56

8

182

3

2 to 4 hours...

57

-1

47

-1

182

3

4 to 6 hours...

56

-2

49

1

171

-8

6 to 8 hours...

56

-2

48

0

170

-9

Total...

232

0

200

8

705

-11

1Expressed as creatinine.

2Sample included amount for about 1 3/4 hours, without food, preceding experiment.

3Subject drank beef tea in 17 minutes, finishing 25 minutes after the beginning of this period.

Table 89. - A. H. M., April 29, 1907. Sitting. (2-Hour Periods). Beef Tea (22° C)

Amount, 1,143 grams; nitrogen, 2.78 grams; total energy, 116 cals. Fuel value: Total, 91 cals.; from protein, 79 p. ct.; from fat, 11 p. ct.; from carbohydrates, 10 p. ct. Basal values (March 6 and 9, 1907): CO2, 51 grams; O2, 46 grams; heat, 164 cals. Nitrogen in urine, 1.06 grams per 2 hours (April 29, 1907).

Time elapsed since subject finished eating.

Nitrogen in urine per 2 hours.

Carbon dioxide.

Oxygen.

Heat.

Total.

Increase.

Total.

Increase.

Total.

Increase.

grams.

grams.

grams.

grams.

grama.

cals.

cals.

0 to 2 hours1..

1.542

62

11

51

5

182

18

2 to 4 hours. .

1.11

54

3

50

4

165

1

4 to 6 hours..

1.11

51

0

46

0

158

-6

6 to 8 hours. .

.93

52

1

44

-2

164

0

Total...

....

219

15

191

7

669

13

1Subject finished drinking beef tea 14 minutes after the beginning of this period. The drinking occupied 12 minutes. 2Computed from amount for 67 minutes in latter portion of period.

Table 90. - A. W. W., May 2, 1907. Sitting. (2-Hour Periods). Beef Tea (1,418 Grams, 22° C; 643 Grams, 7° C)

Amount, 2,056 grams; nitrogen, 4.27 grams; total energy, 185 cals. Fuel value: Total, 148 cals.; from protein, 75 p. ct.; from fat, 13 p. ct.; from carbohydrates, 12 p. ct. Basal values (March 15 and 21, 1907): CO2, 50 grams; O2, 41 grams; heat, 155 call. Nitrogen in urine, 0.81 gram per 2 hours (May 2, 1907).

Time elapsed since subject finished eating.

Nitrogen in urine per 2 hours.

Carbon dioxide.

Oxygen.

Heat.

Total.

Increase.

Total.

Increase.

Total.

Increase.

grama.

grams.

grama.

grams.

grama.

cals.

cals.

0 to 2 hours1..

1.042

62

12

53

12

191

36

2 to 4 hours..

0.17

52

2

36

-5

136

-19

4 to 6 hours..

1.35

50

0

43

2

150

-5

6 to 8 hours..

1.17

50

0

40

-1

147

-8

Total...

....

214

14

172

8

624

4

1Subject finished drinking beef tea 38 minutes after the beginning of this period. The drinking occupied 15 minutes. 2Computed from amount for 52 minutes in latter portion of period.

Table 91. - A. W. W., May 9, 1907. Sitting. (2-Hour Periods). Beef Tea (54° C)

Amount, 1,605 grams; nitrogen, 6.82 grams; total energy, 264 cals.

Fuel value: Total, 204 cals.; from protein, 86 p. ct.; from fat, 7 p. ct.; from carbohydrates. 7 p. ct. Basal values (March 15 and 21, 1907): CO2, 50 grams; O2, 41 grams; heat, 155 cab.

Time elapsed since subject finished eating.

Nitrogen in urine per

2 hours.

Carbon dioxide.

Oxygen.

Heat.1

Total.

Increase.

Total.

Increase.

Total.

Increase.

grams.

grams.

grams.

grams.

grams.

cals.

cals.

0 to 2 hours2..

1.363

63

13

51

10

170

15

2 to 4 hours..

1.363

59

0

43

2

169

14

4 to 6 hours..

1.18

53

3

36

-5

151

-4

6 to 8 hours. .

1.18

51

1

43

2

152

-3

Total...

226

26

173

9

642

22

1Heat eliminated corrected for change in body-weight, but not for change in body-temperature. 2Subject finished drinking beef tea 33 minutes after beginning of this period. The drinking occupied 18 minutes. 3Sample included amount for 1 1/4 hours, without food, preceding experiment.

Table 92. - A. H. M., May 10, 1907. Sitting. (2-Hour Periods). Beef Tea (50° C)

Amount, 892 grams; nitrogen, 3.79 grams; total energy, 147 cals.

Fuel value: Total, 113 cals.; from protein, 86 p. ct.; from fat, 7 p. ct.; from carbohydrates, 7 p. ct. Basal values (March 6 and 9, 1907): CO*, 51 grams; O2, 46 grams; heat (computed), 152 cals.

Time elapsed since subject finished eating.

Nitrogen in urine per 2 hours.

Carbon dioxide.

Oxygen.

Heat (computed).

Total.

Increase.

Total.

Increase.

Total.

Increase.

grams.

grams.

grams.

grams.

grams.

cals.

cals.

0 to 2 hours1..

1.62*

65

14

54

8

182

30

2 to 4 hours..

1.59

53

2

42

-4

141

-11

4 to 6 hours..

1.19

54

3

50

4

165

13

6 to 8 hours..

1.19

52

1

41

-5

140

-12

Total...

224

20

187

3

628

20

1Subject finished drinking beef tea 20 minutes after the beginning of this period. The drinking occupied 8 minutes. 2Sample included amount for about 1 1/2 hours, without food, preceding experiment.

Table 93. - J. J. C, May 12, 1910. Sitting. (1-Hour Periods). Beef Tea (988 Grams, 15.5° C.; 290 Grams, 38° C)

Amount, 1,222 grams; nitrogen, 5.62 grams; total energy, 214 cals. Fuel value: Total, 165 cals.; from protein, 87 p. ct.; from fat, 7 p. ct.; from carbohydrates, 6 p. ct. Nitrogen in urine, 1.03 grams per hour (in first two periods).1 Basal values (May 12, 1910): CO2, 25 grams; O2, 20 grams; heat,1 79 cals.; respiratory quotient, 0.92. Nitrogen in urine, 0.34 gram per hour.

Time elapsed since subject finished eating.

Carbon dioxide.

Oxygen.

Heat.2

Respiratory quotient.

Total.

Increase.

Total.

Increase.

Total.

Increase.

grams.

grams.

grams.

grams.

cals.

cals.

1/2 to 1 1/2 hours......

30.5

5.5

25.0

5.0

79

0

0.90

1 1/2 to 2 1/2 hours......

28.5

3.5

25.5

5.5

84

5

.82

2 1/2 to 3 1/2 hours......

27.5

2.5

23.5

3.5

76

-3

.85

3} to 4} hours......

25.0

0.0

22.5

2.5

76

-3

.80

Total.........

111.5

11.5

96.5

16.5

315

-1

....

1Sample obtained previous to these periods, but also following the ingestion of beef tea, contained 0.85 gram nitrogen per hour. 2Heat eliminated corrected for change in body-weight, but not for change in body-temperature.