Scurvy develops gradually. The sufferer loses weight, is anemic, pale, weak and short of breath. The gums become swollen, bleed easily, and frequently ulcerate. The teeth loosen and may drop out. Necrotic areas in the jaw bone may result. Hemorrhages into the mucous membranes and the skin are characteristic. In the skin large blue-black spots develop after trivial injury, or even spontaneously. The ankles become edematous, and in severe cases there develops a hard, board-like condition of the skin and subcutaneous tissues. Nervous symptoms of various types are seen, some of which are the result of the rupture of blood-vessels. There follows in the later stages of the disease, headache, convulsions and delirium.