Pharmacodynamics According To The Several Systems
Description
This section is from the book "Laboratory Manual Of Pharmacology", by A. D. Bush. Also available from Amazon: Laboratory manual of pharmacology.
Pharmacodynamics According To The Several Systems
Central Nervous System.
Cerebrum. | |
Stimulation. | Depression. |
(Cannabis) | Cannabis |
(Cocaine) | (Cocaine) |
(Atropine) | Chloral |
Tobacco | |
Atropine | |
Chloroform | |
Cerebellum. | |
Stimulation. | Depression. |
Tobacco | Alcohol |
(Cocaine) | Cocaine |
Morphine | |
Ether | |
Chloroform | |
Antimony | |
Atropine | |
Bromides | |
Medulla. | |
Caffeine | Alcohol |
Chloral | |
Morphine | |
Strychnine | Cocaine |
Atropine | |
(Cocaine) | |
(Atropine) | |
Ether and Chlor. | |
Bromides | |
Antimony | |
Quinine | |
Spinal Cord. | |
Strychnine | Alcohol |
Caffeine | Chloral |
Morphine | Morphine |
Veratrine | Cocaine |
Atropine | |
Aspidium | Pilocarpine |
Santonin | Physostigmine |
NH4CI (hypo.) | Ether and Chlor. |
(Atropine) | Antimony |
(Cocaine) | Bromides |
Quinine | |
Muscular System. | |
Voluntary. | |
Stimulation. | Depression. |
Caffeine | Tobacco |
Veratrum | Physostigmin |
Aconite | |
Antimony | |
Quinine | |
Involuntary. | |
Stimulation. | Depression. |
Strychnine | Atropine |
Physostigmine | Antimony |
Pilocarpine | Lead |
Quinine | |
Stimulation. | Locus of action. |
Strychnine | Centric |
Caffeine | Centric |
Cocaine | Centric |
Atropine | Centric |
(Antimony) | Centric |
(Quinine) | Centric |
Depression. | Locus of action. |
Chloral | Centric |
Morphine | Centric |
Cannabis | Centric |
Pilocarpine | Local |
Physostigmine | Centric |
Ether and Chlor. | Centric |
Veratrum | Centric |
Antimony | Local |
Bromides | Central |
Acetphenetidin | Centric |
Centric | |
Colchicum | Reflex |
Aspidium | Centric |
Heart. | |||
Stimulation. | Depression. | ||
Caffeine | C. | (Caffeine) | L. |
Cocaine | L. | Chloral | L. |
Atropine | L. | Morphine | C. |
Epinephrin | L. | Tobacco | L. |
(Ergot) | L. | Pilocarpine | L. |
(Digitalis) | L. | Physostig. | L. |
Ether | L. | ||
Chloroform | L. | ||
Epinephrin | C. | ||
Ergot | C. & L. | ||
Digitalis | C. | ||
Aconite | C. & L. | ||
Veratrum | C. | ||
Antimony | L. | ||
Acetphenet. | L. | ||
Ac. Salicyl. | L. | ||
Aspidium | C. | ||
Pituitary | C. | ||
Blood-pressure. | |||
Stimulation. | Depression. | ||
Strychnine | C. | Cocaine (2) | L. |
Caffeine | C. | Ether | L. |
Cocaine (1) | C. | Chloroform | L. |
Atropine | C. | Nitroglyc. | L. |
Pilocarpine | L. | Aconite | L. & C. |
Physostig. | L. | Veratrum | R. |
Epinephrin | L. | Antimony | R. |
Ergot | L. | Ipecac | L. |
Digitalis | C. | Aspidium | C. |
Ac. Salicyl. | L. | ||
NH4OH | R. | ||
Pituitary | L. | ||
Secretory Glands. | |||
Stimulated. | Depressed. | ||
C. | Morphine | C. | |
Pilocarpine | P. | Tobacco | P. |
Tobacco | P. | Cocaine | C. |
Physostig. | P. | Atropine | L. |
Aconite | L. | Lead | C. |
Antimony | L. | ||
L. | |||
Metabolism. | |
Increased. | Diminished. |
Strychnine | Alcohol |
Caffeine | Morphine |
Chloral | Quinine |
Atropine | |
Veratrum | |
Antimony | |
Ac. Salicyl. | |
Ipecac | |
Thyroid | |
Alimentary Tract. | |
Stimulation. | Depression. |
Aconite | |
Caffeine | Alcohol |
Apomorphine | |
Strychnine | Chloral |
Digitalis | |
Irritation.
Ac. Salicylic, Antimony Arsenic, Bromides Castor oil, Colchicine Croton oil, Ipecac Lead, Mercury NH4HCO3, Rhubarb Veratrum, xanthracene purges.
Peristalsis. | |
Increased. | Diminished. |
Cocaine (small) | Cocaine (large) |
Pilocarpine | Atropine |
Physostigmine | Epinephrin |
Purges | Ergot |
Salines | |
Veratrum | |
Kidney. | |
Stimulated. | Depressed. |
Caffeine | Quinine |
Cocaine | Atropine |
Ac. Salicylic. | |
(Digitalis) | |
Irritated. | |
Ipecac | Mercury |
Sweat Glands. | |
Stimulated. | Depressed. |
Aconite | Atropine |
Ac. Salicylic. | Bromides |
Antimony | |
Pilocarpine | |
Physostigmine | |
Veratrum | |
Salivary Glands. | |
Stimulated. | Depressed. |
Pilocarpine | Atropine |
Physostigmine | |
Antimony | |
Mercury | |
Eye.
Contraction.
Morphine, depression cerv. symp. (?) Chloroform, depression cerv. symp. Ether, depression cerv. symp. Ergot, stimulation 3d nerve. Physostig., stimulation 3d nerve. Pilocarpine, stimulation 3d nerve.
Pupil.
Dilatation.
Atropine, paralysis circularis. Cannabis, depression 3d n. (?) Cocaine, stimulation cerv. symp. Chloroform, depression 3d nerve. Ether, depression 3d nerve. Epinephrin, stimulation cerv. symp.
Temperature. | Absorption. | Elimination. | |
Increased. | Rapid. | Rapid. | |
Atropine | C. | Aconite | Acetphenetidin |
Acetphenetidin | Caffeine | ||
Diminished. | Ac. Salicylic. | ||
Ac. Salicylic. | C. | Alcohol | Slow. |
Acetphenetidin | c. | Apomorphine | Ac. Salicylic. |
Aconite | c. | Arsenic | Antimony |
Alcohol | p. | Atropine | Arsenic |
Antimony | R. | Bromides | Bromides |
Apomorphine | R. | Caffeine | Digitalis |
Camphor | C.(?) | Chloral | Iodides |
Chloral | c. | Cocaine | Lead |
Digitalis | c. | Mercury | Mercury |
Ether | s. | Iodides | Quinine |
Chloroform | s. | Lead | Strychnine |
Morphine C. & P. | Morphine | ||
Pilocarpine | P. | Physostigmine | |
Pilocarpine | |||
Quinine | |||
Santonin | |||
Strychnine | |||
Slow. | |||
Aspidium | |||
Antimony | |||
Digitalis | |||
Ipecac | |||
Phosphorus | |||
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