This section is from the book "Laboratory Manual Of Pharmacology", by A. D. Bush. Also available from Amazon: Laboratory manual of pharmacology.
Nux Vomica consists of the dried ripe seeds of Strychnos Nux-vomica (Fam. Loganiaceae), a small tree indigenous to Indo-Asia. It owes its activity principally to the alkaloid strychnine, of which it contains about 2.5%.
Properties:
Mux Vomica: | Strych. Sulph.: |
Appearance ........................................................................................ | Appearance ....................................................................................... |
Color ......................................................................................................... | Color ......................................................................................................... |
Odor............................................................................................................ | Odor............................................................................................................ |
Taste ......................................................................................................... | Taste .................................................................................................... |
Sol.: H20........................................................................................ | Sol.: H2O .......................................................................................... |
Incompatibilities: To Tincture Nux Vomica add | |
An hydroxide ........................................................................................ | An iodide ................................................................................................. |
A carbonate ......................................................................................... | Ac. Tannic ................................................................. |
A bromide .............................................................................................. | |
Test for Strychnine: In 1 mil H2SO4 place 0.05 Gm. Strychnine; then drop in a small fragment of K2CrO7; five sequent color changes should be noted:...................
................................................................................................................................................
Nux Vomica is used as a bitters. Dose, 0.06 Gm. Strychnine is used to heighten the excitability of the spinal reflexes. Dose, of Strychnine or of the Nitrate or Sulphate, 0.0015 Gm.
Official preparations are: the Extract, the Fluidextract, and the Tincture.
 
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